ISU201 Enhances the Resolution of Airway Inflammation in a Mouse Model of an Acute Exacerbation of Asthma

Figure 3

Effects of drug treatment on production of proinflammatory cytokines (a) CXCL1, (b) CCL11, (c) IL-6, and (d) TNF-α in BAL fluid. Animals were treated with vehicle (—●—), ISU201 (- -□- -), or dexamethasone (⋯○⋯) at 2 and 8 hours after induction of an exacerbation. Data are mean ± SEM ( animals per group). Significant differences relative to vehicle-treated animals at each time point are shown as (), (), and ().

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