Mediators of Inflammation

Research Article

Short-Term Reproducibility of the Inflammatory Phenotype in Different Subgroups of Adult Asthma Cohort

Table 1

Characteristic of study participants: steroid-naïve asthma (SN), mild to moderate asthma (MMA), and refractory asthma (RA) cohorts. Values are presented as mean ± SD.


	SN group	MMA group	RA group

	17	33	16
Age (years)	33.41 ± 11.26	47.52 ± 13.9^***	50.5 ± 9.96^***
Sex F : M	11 : 6	16 : 17	11 : 5
History of asthma (years)	5.96 ± 8.86	10.24 ± 12.9	23.68 ± 11.3^***
Positive SPT ()	14	21	16
FEV₁ (actual/% of predicted value)	3.32 ± 0.91/92.4 ± 13.9	2.69 ± 0.86^*/83.06 ± 14.7	1.79 ± 0.61^***/58.94 ± 11.8
FEV₁/FVC (%)	73.35 ± 8.19^***	70.6 ± 8.6	61.63 ± 11.48^**
Mean dose of ICS (µg)^†	0	1373.12 ± 908.8	1307.5 ± 586
Mean dose of OCS (mg)^‡	0	0	17.75 ± 7.96

SPT, skin prick tests; FEV₁, forced expiratory volume in one second; FVC, forced vital capacity; ICS, inhaled corticosteroids; OCS, oral corticosteroids.
^†Equivalent to CFC-beclomethasone dipropionate.
^‡Equivalent to prednisone.
values: age: ^*** versus SN; history of asthma: ^*** versus SN and MMA; FEV₁: ^* versus SN, ^*** versus SN and MMA; FEV₁/FVC: ^** versus MMA, ^*** versus RA.