Research Article

Short-Term Reproducibility of the Inflammatory Phenotype in Different Subgroups of Adult Asthma Cohort

Table 3

The cellular profile of sputum, asthma phenotypes, and ACQ score at visit 2. Values are presented as mean ± SD.

SN groupMMA groupRA group

Sputum cytology
 Total cells (×106/mL)5.41 ± 7.477.21 ± 15.95.18 ± 4.14
 Viability (%)81.78 ± 13.7281.9 ± 10.180.52 ± 10.76
 Squamous cells (%)4.36 ± 4.216.92 ± 7.33 8.31 ± 6.04
 Epithelial cells (%)0.9 ± 0.670.7 ± 0.521.1 ± 0.78
 Macrophages (%)60.42 ± 14.4753.45 ± 20.5257.25 ± 10.91
 Lymphocytes (%)4.03 ± 3.45.83 ± 8.636.75 ± 4.21
 Neutrophils (%)26.48 ± 16.7828.35 ± 21.5225.25 ± 14.65
 Eosinophils (%)4.68 ± 6.425.03 ± 6.522.5 ± 2.94
Inflammatory phenotype, (%)
 Eosinophilic10 (59%) 19 (58%)7 (44%)
 Neutrophilic1 (6%)1 (3%)1 (6%)
 Paucigranulocytic6 (35%) 11 (33%)8 (50%)
 Mixed granulocytic0 2 (6%)0
ACQ score0.9 ± 0.591.37 ± 1.052.48 ± 0.89***

SN, steroid- naïve asthma; MMA, mild to moderate asthma; RA, refractory asthma. *** versus MMA group and SN group.