Anti-HMGB1 Monoclonal Antibody Ameliorates Immunosuppression after Peripheral Tissue Trauma: Attenuated T-Lymphocyte Response and Increased Splenic CD11b⁺Gr-1⁺ Myeloid-Derived Suppressor Cells Require HMGB1

Figure 2

Time course of plasma HMGB1 level after pseudofracture (PF). Western blot of HMGB1 in plasma at time points after PF. LPS-stimulated macrophages were used as positive controls (lanes 11-12). Control mouse was used as time 0. mice per time point.