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Mediators of Inflammation
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Mediators of Inflammation
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2015
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Article
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Tab 1
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Research Article
Blockade of the JNK Signalling as a Rational Therapeutic Approach to Modulate the Early and Late Steps of the Inflammatory Cascade in Polymicrobial Sepsis
Table 1
SP600125 effects on lung histologic damage in CLP mice.
is for
.
Parameters
Sham
CLP
CLP + SP600125
Lung
Inflammatory infiltrate
0
2.31 ± 0.41
1.28 ± 0.23
***
Vascular congestion
0
2 ± 0.18
1.1 ± 0.37
***
Interstitial edema
0
2.12 ± 0.53
1.32 ± 0.44
***
Liver
Inflammatory infiltrate
0
2.1 ± 0.39
1.3 ± 0.33
***
Steatosis
0
2.89 ± 0.56
1.56 ± 0.26
***
Necrosis
0
2.2 ± 0.47
0.9 ± 0.21
***
Ballooning degeneration
0
2.76 ± 0.47
1.58 ± 0.48
***