Clinical Study

Effects of Oral L-Carnitine on Liver Functions after Transarterial Chemoembolization in Intermediate-Stage HCC Patients

Table 5

Subgroup analysis in BCAA+ and BCAA− patients.

Parameter (mean ± SD) PretreatmentAfter TACE
1 week4 weeks12 weeks

BCAA+ ()CP score6.14 ± 1.046.43 ± 0.996.04 ± 1.036.24 ± 1.36
S. albumin (g/dL)3.18 ± 0.562.90 ± 0.483.25 ± 0.533.10 ± 0.49
PT (%)87.32 ± 18.9988.50 ± 17.6991.59 ± 18.1988.13 ± 16.96
T. bilirubin (mg/dL)1.05 ± 0.591.10 ± 0.581.00 ± 0.561.22 ± 0.72
ALT (IU/L)37.07 ± 16.5048.68 ± 24.9535.89 ± 15.4337.16 ± 11.05
AST (IU/L)52.04 ± 22.9748.93 ± 24.6550.79 ± 19.3953.20 ± 18.43
GGTP (IU/L)69.89 ± 72.7486.36 ± 100.4189.26 ± 82.7753.16 ± 36.19

BCAA− group ()CP score5.73 ± 0.935.90 ± 0.835.73 ± 0.766.05 ± 1.23
S. albumin (g/dL)3.41 ± 0.553.12 ± 0.563.38 ± 0.613.40 ± 0.60
PT (%)88.9 ± 17.288.8 ± 18.289.5 ± 16.589.9 ± 18.0
T. bilirubin (mg/dL)0.88 ± 0.380.99 ± 0.460.89 ± 0.431.02 ± 0.58
ALT (IU/L)37.86 ± 32.0449.81 ± 32.6038.00 ± 26.6534.15 ± 20.24
AST (IU/L)57.36 ± 42.0352.62 ± 34.7360.27 ± 38.9157.25 ± 46.66
GGTP (IU/L)66.59 ± 76.0690.05 ± 127.71100.82 ± 154.5070.50 ± 82.04

SD: standard deviation; CP: Child-Pugh; S. albumin: serum albumin; PT: prothrombin time; T. bilirubin: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGTP: gamma-glutamyl transpeptidase; TACE: transarterial chemoembolization.
Significant difference compared with baseline value; significant difference compared with 1 week after TACE; significant difference compared with 4 weeks after TACE; ; ; .