Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells

Figure 7

Effects of IL27, calprotectin, and IL27 + calprotectin cotreatment on STAT1/3 phosphorylation. Relative protein levels of Tyr701-phosphorylated pSTAT1 (a) and Tyr705-pSTAT3 (b) in IL27 (30 ng/mL) ± calprotectin (1 μg/mL)-stimulated HUVECs for 3, 6, 12, and 24 h performed by western blot. Values are represented as mean ± SEM. Normalization was performed against tubulin. Presented statistical significances are between IL27 and IL27 + calprotectin and the indicated values correspond to .

(a)

(b)