The Expression of TLR-9, CD86, and CD95 Phenotypes in Circulating B Cells of Patients with Chronic Viral Hepatitis B or C before and after Antiviral Therapy

Table 1

Demographic characteristics and clinical features of participants.

Parameters	HBV	HCV	Healthy controls
Number	35	50	17
Age (years)
Mean ± SD	45 ± 10	43 ± 10	44 ± 9
Median (range)	40 (19–62)	45 (27–69)	49 (42–54)
Sex (%)
Male	30 (85,8)	29 (48)	9 (52,9)
Female	5 (14,2)	21 (42)	8 (47,1)
Viremia (log10 copies/mL)
Median (range)	8,4 (5,7–9,8)^*	5,9 (1,2–7,5)^*	NA
ALT (U/L)
Median (range)	219 (12–914)^*	44,1 (11,2–274,90)^*	16 (4–29)
AST (U/L)
Median (range)	117 (22–221)^*	44,6 (13,9–262)^*	16 (8–32)
HBsAg (IU/mL)
Median (range)	4697,68 (1243,65–55925,04)^*	/	NA
HBsAb (mIU/mL)
Median (range)	0,06 (0–3,71)^*		NA
HBeAg (S/CO)
Median (range)	3233,3 (3,88–4094,10)^*	/	NA
HBeAb (S/CO)
Median (range)	16.74 (0,02–46,74)^*		NA

Normal values: ALT ≤ 40 IU/L; AST ≤ 40 IU/L; HBV DNA ≤ 3 log₁₀copies/mL; HCV RNA ≤ 3 log₁₀copies/mL; < 0.05 HBV/HCV versus healthy controls.