Research Article

The Transcription Factor ZNF395 Is Required for the Maximal Hypoxic Induction of Proinflammatory Cytokines in U87-MG Cells

Table 2

Functional annotation clustering of genes activated (>1.49, ) by ZNF395 under hypoxia in U87-MG cells that were identified by microarray; annotation clusters with an enrichment score of 2.5 are shown. The adjusted value indicates the significance of enrichment.

Pathway valueGene symbol

Response to wounding3.6 10−5NLRC4, IL-6, SERPINA10, LIPA, MTPN, IL-1β, C1S, TIMP3, PLAU
Regeneration6.34 10−5LIF, SERPINA10, MTPN, TIMP3, PLAU
Wound healing 3.3 10−4IL-6, SERPINA10, MTPN, IL-1β, TIMP3, PLAU
Development growth 0.0025SERPINA10, MTPN, TIMP3, PLAU