Review Article
Role of IL-38 and Its Related Cytokines in Inflammation
Table 1
IL-1 family members [
10,
11].
| Cytokine | Family name | Receptor | Coreceptor | Property |
| IL-1 | IL-1F1 | IL-1RI | IL-1RAcp | Proinflammatory | IL-1 | IL-1F2 | IL-1RI | IL-1RAcp | Proinflammatory | IL-1Ra | IL-1F3 | IL-1RI | NA | Antagonist for IL-1, IL-1 | IL-18 | IL-1F4 | IL-18Rα | IL-18R | Proinflammatory | IL-36Ra | IL-1F5 | IL-36R | NA | Antagonist for IL-36, IL-36, and IL-36 | IL-36 | IL-1F6 | IL-36R | IL-1RAcp | Proinflammatory | IL-37 | IL-1F7 | IL-18R? | Unknown | Anti-inflammatory, transcription regulating factor [12] | IL-36 | IL-1F8 | IL-36R | IL-1RAcp | Proinflammatory | IL-36 | IL-1F9 | IL-36R | IL-1RAcp | Proinflammatory | IL-38 | IL-1F10 | IL-36R | Unknown | Antagonist for IL-36, IL-36, and IL-36 | IL-33 | IL-1F11 | ST2 | IL-1RAcp | Proinflammatory, transcription regulating factor [13] |
|
|
NA: not applicable; ?: requires confirmation.
|