Role of Genetic Alterations in the <i>NLRP3</i> and <i>CARD8</i> Genes in Health and Disease

<div>Schematic representation of polymorphism in the<i> CARD8</i> gene and mRNA isoforms (modified from Bagnall et al. 2008 [<a href="/journals/mi/2015/846782/#B45">45</a>]; not to scale). Exons of the<i> CARD8</i> gene are displayed as white boxes. The arrow (<b>→</b>) represents the site of open reading frame (ORF) for the given isoforms.</div>

Mediators of Inflammation

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Figure 2

Figure 2: Role of Genetic Alterations in the <i>NLRP3</i> and <i>CARD8</i> Genes in Health and Disease 

Mediators of Inflammation

Role of Genetic Alterations in the NLRP3 and CARD8 Genes in Health and Disease

Figure 2