Research Article
Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats
Table 1
Effect of thymoquinone (TQ) on change () of total body weight (wt), organ/total wt ratios, and kidney and liver function tests in methotrexate- (MTX-) induced toxicity.
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Kidney/wt and liver/wt are ratios of weight of respective organ/total body weight 1000 ratio. BUN; blood urea nitrogen, ALT; alanine aminotransferase, and AST; aspartate aminotransferase. Values are representation of 8–11 observations as means ± SEM. Results are considered significantly different when . aSignificant difference compared to control, bsignificant difference compared to MTX group, and cno significant difference compared to control. |