Research Article
Dexamethasone Suppressed LPS-Induced Matrix Metalloproteinase and Its Effect on Endothelial Glycocalyx Shedding
Table 1
Comparison of blood gas analysis (mean ± SD).
| | Variables | Control | Dex. | LPS | LPS + Dex. | LPS + Doxy. |
| | Lactate, mmol/L | 1.9 ± 0.3 | 2.3 ± 0.4 | 6.1 ± 3.7 | 2.3 ± 0.7 | 2.7 ± 0.9 | | pH | 7.36 ± 0.03 | 7.38 ± 0.07 | 7.18 ± 0.12 | 7.39 ± 0.04 | 7.36 ± 0.06 | | BE, mmol/L | 5.3 ± 2.9 | 6.3 ± 0.9 | 2.4 ± 7.1 | 4.4 ± 1.2 | 4.3 ± 1.0 | | PaCO2, mmHg | 57.9 ± 10.8 | 57.1 ± 13.5 | 66.8 ± 4.4 | 50.6 ± 5.4 | 57.6 ± 10.2 | | SaO2, % | 87.8 ± 10.1 | 88.3 ± 9.2 | 77.9 ± 4.3 | 94.0 ± 3.4 | 86.0 ± 8.7 |
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Compared with group endotoxin, ; ; .
BE, base excess; PaCO2, arterial carbon dioxide pressure, SaO2, arterial oxygen saturation.
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