Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response

<div>The number of genes in lung myofibroblasts with significant changes in expression at varying time points following Thy1 stimulation. Graphic presentation of GeneChip microarray results obtained from primary myofibroblast RNA extracts following stimulation with G7 anti-Thy mAb (5 <i>μ</i>g/mL) or control IgG isotype for 30 min, 1 h, 6 h, or 24 h. The microarray data were processed by volcano analysis. Upregulated genes (blue), downregulated genes (red).</div>

Mediators of Inflammation

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Figure 2: Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response 

Figure 2 | Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response 