Mediators of Inflammation / 2015 / Article / Tab 1 / Research Article
Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response Table 1 Molecular pathways downregulated by Thy1.
Pathway name # input genes in the pathway Long adhesion 13 Long-term depression 6 ECM-receptor interaction 6 Small cell lung cancer 5 0.004769 Regulation of actin cytoskeleton 8 0.005003 Prostate cancer 5 0.005006 Tight junction 6 0.007175 Melanoma 4 0.012134 Bladder cancer 3 0.015551 MAPK signaling pathway 8 0.016136 Axon guidance 5 0.022646 Endometrial cancer 3 0.027335 mTOR signaling pathway 3 0.027335 Gap junction 4 0.02851 Insulin signaling pathway 5 0.029243 Non-small cell lung cancer 3 0.030129 GnRH signaling pathway 4 0.031564 Alzheimer’s disease 2 0.033214 Wnt signaling pathway 5 0.03603 p53 signaling pathway 3 0.048047 Glioma 3 0.048047 Cell cycle 4 0.048272 B cell receptor signaling pathway 3 0.049885 Long-term potentiation 2 0.049885 Neurodegenerative diseases 2 0.050764 Wnt signaling pathway 7 0.001962 B cell receptor signaling pathway 4 0.00836 VEGF signaling pathway 4 0.011283 Natural killer cell mediated cytotoxicity 5 0.01976 Hedgehog signaling pathway 3 0.026203 Neuroactive ligand-receptor interaction 7 0.036606 T cell receptor signaling pathway 4 0.037492 Dorsoventral axis formation 2 0.039028
