Research Article

Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis

Table 2

Balance between IL-1β receptors types 1 and 2 in terms of expression of membrane-bound forms of receptors on intact cells and monocytes in 24 h spontaneous and LPS-stimulated PBMC cultures in healthy individuals and in patients with rheumatoid arthritis in the acute phase ( = 33) and after response to treatment ( = 23). Each table cell indicates the more highly expressed receptor for a selected subpopulation in a studied group. “=” denotes that no significant difference in receptor expression was observed.

In terms of percentage of cellsIn terms of the number of receptors
Healthy individualsRA patients in acute phaseRA patients after response to treatmentHealthy individualsRA patients in acute phaseRA patients after response to treatment

T cellsIL-1R1==IL-1R1==
B cellsIL-1R1==IL-1R1==
MonocytesIL-1R1==IL-1R2==
Monocytes in spontaneous culturesIL-1R1IL-1R1IL-1R1===
Monocytes in LPS-stimulated culturesIL-1R1IL-1R1IL-1R1IL-1R1==