Bone Marrow Mesenchymal Stem Cells Inhibit Lipopolysaccharide-Induced Inflammatory Reactions in Macrophages and Endothelial Cells

Figure 2

Coculture with BMSCs attenuates the activity of LPS to induce expressions of TLR2, TLR4, and p65 in alveolar macrophages (a) and HUVECs (b) at the protein level. The total proteins were extracted from the cultured alveolar macrophages and HUVECs treated (1) PBS control, (2) BMSCs, (3) LPS, and (4) BMSCs and LPS. The expressions of TLR2, TLR4, and p-NF-κB p65 were determined by Western blot. The density of specific bands was quantitated. Data are expressed as the mean ± SD from three experiments. , .

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