Blood Genome-Wide Transcriptional Profiles of HER2 Negative Breast Cancers Patients

Figure 4

Heat map of the significant canonical pathways in the four datasets of differentially expressed genes: BC versus CTR, ER+PR+HER− versus CTR, TNBC (ER−PR−HER−) versus CTR, and TNBC versus ER+PR+HER− subgroup. The significance of the association between canonical pathways and each dataset was assessed in IPA by Fischer’s exact test (). The darkest color was assigned to the smallest value for a canonical pathway among all datasets, while uncolored boxes indicate the nonsignificant canonical pathways (ns) or their absence (N/A).