A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets

Figure 2

TLR ligation induces differential cytokine production by human blood DCs. The DCs were stimulated as indicated and cultured overnight at 37°C. IL-10 and IL-12p70 production was analyzed in supernatants of overnight cultures by standard sandwich ELISA (). Each symbol represents one donor (also across the subsets). Significance was determined by Kruskal-Wallis test followed by Dunn’s testing comparing different conditions of the same subset (; ).