Research Article
Interleukin-27 as a Novel Biomarker for Early Cardiopulmonary Failure in Enterovirus 71-Infected Children with Central Nervous System Involvement
Table 2
Genotype and allele frequencies of IL27p28 polymorphism in EV71-infected patients and controls.
| SNP | Genotype and allele | EV71-infected patients (), (%) | Controls (), (%) | | values | Unadjusted OR (95% CI) |
| rs153109 | TT | 57 (44.88) | 42 (44.21) | 0.010 | 0.921 | 1.028 (0.602–1.755) | CT | 56 (44.09) | 43 (45.26) | 0.030 | 0.862 | 0.9538 (0.559–1.628) | CC | 14 (11.02) | 10 (10.53) | 0.014 | 0.906 | 1.053 (0.446–2.486) | T | 170 (66.93) | 127 (66.84) | 0.000 | 0.985 | 1.004 (0.673–1.497) | C | 84 (33.07) | 63 (33.16) | 0.000 | 0.985 | 0.996 (0.668–1.485) |
| rs17855750 | TT | 110 (86.61) | 85 (89.47) | 0.416 | 0.519 | 0.761 (0.332–1.748) | GT | 17 (13.39) | 10 (10.53) | 0.416 | 0.519 | 1.314 (0.572–3.016) | T | 237 (93.31) | 180 (94.74) | 0.389 | 0.533 | 0.775 (0.346–1.732) | G | 17 (6.69) | 10 (5.26) | 0.389 | 0.533 | 1.291 (0.557–2.888) |
| rs181206 | TT | 111 (87.40) | 83 (87.37) | 0.000 | 0.994 | 1.003 (0.450–2.234) | TC | 16 (12.60) | 12 (12.63) | 0.000 | 0.994 | 0.997 (0.448–2.221) | T | 238 (93.70) | 178 (93.68) | 0.000 | 0.994 | 1.003 (0.463–2.173) | C | 16 (6.30) | 12 (6.32) | 0.000 | 0.994 | 0.997 (0.460–2.161) |
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