Interleukin-27 as a Novel Biomarker for Early Cardiopulmonary Failure in Enterovirus 71-Infected Children with Central Nervous System Involvement

Table 2

Genotype and allele frequencies of IL27p28 polymorphism in EV71-infected patients and controls.

SNP	Genotype and allele	EV71-infected patients (), (%)	Controls (), (%)		values	Unadjusted OR (95% CI)
rs153109	TT	57 (44.88)	42 (44.21)	0.010	0.921	1.028 (0.602–1.755)
	CT	56 (44.09)	43 (45.26)	0.030	0.862	0.9538 (0.559–1.628)
	CC	14 (11.02)	10 (10.53)	0.014	0.906	1.053 (0.446–2.486)
	T	170 (66.93)	127 (66.84)	0.000	0.985	1.004 (0.673–1.497)
	C	84 (33.07)	63 (33.16)	0.000	0.985	0.996 (0.668–1.485)
rs17855750	TT	110 (86.61)	85 (89.47)	0.416	0.519	0.761 (0.332–1.748)
	GT	17 (13.39)	10 (10.53)	0.416	0.519	1.314 (0.572–3.016)
	T	237 (93.31)	180 (94.74)	0.389	0.533	0.775 (0.346–1.732)
	G	17 (6.69)	10 (5.26)	0.389	0.533	1.291 (0.557–2.888)
rs181206	TT	111 (87.40)	83 (87.37)	0.000	0.994	1.003 (0.450–2.234)
	TC	16 (12.60)	12 (12.63)	0.000	0.994	0.997 (0.448–2.221)
	T	238 (93.70)	178 (93.68)	0.000	0.994	1.003 (0.463–2.173)
	C	16 (6.30)	12 (6.32)	0.000	0.994	0.997 (0.460–2.161)