An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons

Figure 3

Inhibitory effects of PKA inhibitor on EP2 receptor agonists-induced potentiation of . (a, b) KT5720 (10 μM) inhibited ONO-AE1-259 (10 μM) or butaprost- (10 μM) induced potentiation of . (c) Averaged amplitude of NMDA-induced outward currents. The columns and bars represent the mean ± SEM ( cells). Asterisks indicate a significant difference between the values (, unpaired t-test). Calibration bars are 50 pA and 20 sec.

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