Research Article
Overexpression of Notch3 and pS6 Is Associated with Poor Prognosis in Human Ovarian Epithelial Cancer
Table 2
Correlation between the protein expression of Notch3 and pS6 proteins and clinicopathological parameters in patients with ovarian epithelial cancer.
| Characteristics | Cases, | Notch3 expression, | value | pS6 expression, | value | | | | | | |
| Age, yrs | | | | | | | | | | 50 | 79 | 7 | 19 | 53 | 0.947 | 6 | 37 | 36 | 0.558 | ≥50 | 41 | 3 | 11 | 27 | 6 | 12 | 23 |
| Clinical stages | | | | | | | | | | III | 41 | 8 | 17 | 16 | 0.000 | 7 | 22 | 12 | 0.001 | IIIIV | 79 | 2 | 13 | 64 | 5 | 27 | 47 |
| Pathological grading | | | | | | | | | | G1 | 17 | 7 | 7 | 3 | 0.000 | 5 | 7 | 5 | 0.001 | G2 | 40 | 3 | 17 | 20 | 6 | 22 | 12 | G3 | 63 | 0 | 6 | 57 | 1 | 20 | 42 |
| Histologic type | | | | | | | | | | Serous cystadenocarcinoma | 77 | 1 | 19 | 57 | 0.006 | 3 | 31 | 43 | 0.011 | Mucinous cystadenocarcinoma | 43 | 9 | 11 | 23 | 9 | 18 | 16 |
| Lymph node metastasis | | | | | | | | | | Yes | 37 | 0 | 5 | 32 | 0.001 | 0 | 5 | 32 | 0.000 | No | 83 | 10 | 25 | 48 | 12 | 44 | 27 |
| Ascites | | | | | | | | | | Yes | 70 | 2 | 9 | 59 | 0.000 | 2 | 21 | 47 | 0.000 | No | 50 | 8 | 21 | 21 | 10 | 28 | 12 |
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