Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses

Figure 1

Blockade of Wnt/β-catenin pathway aggravated the silica-induced lung inflammation. Lung sections from C57BL/6 were stained with H&E and observed under the light microscope (magnifications ×200). Histopathological changes were assessed in saline group (a1–c1), silica group (a2–c2), silica + β-catenin group (a3–c3), and silica + NC shRNA group (a4–c4) at days 7 (a1–a4), 28 (b1–b4), and 56 (c1–c4).