Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses

Figure 7

Blockade of Wnt/β-catenin pathway alleviated silica-induced fibrosis. (a) Lung sections from C57BL/6 were stained with Masson trichrome staining and observed under the light microscope (magnifications ×200). Expressions of GATA3 (b) and IL-4 and IL-13 (c) in the lung were assayed by real-time RT-PCR using the method. Values are shown as mean ± SEM (-5) (, as compared with saline group, ; #, as compared with silica group and silica + NC shRNA group, ).

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