A Novel Oxidative Stress Mediator in Acute Appendicitis: Thiol/Disulphide Homeostasis
Table 1
The demographics and laboratory findings of AA and control groups.
Variables
Acute appendicitis
Control
value
()
()
Gender, (%)
Male
43 (60.6)
30 (42.3)
0.04
Female
28 (39.4)
41 (57.7)
Age (years)
32.4 ± 9.1
30.1 ± 8.9
NS
BMI (kg/m2)
21.7 ± 2.9
23.8 ± 3.1
NS
WBC (μL)
13.5 ± 2.7
7.1 ± 1.5
<0.001
CRP (mg/L)
1.3 (18)
0.6 (3)
<0.001
Hemoglobin (g/dL)
13.6 ± 0.9
13.6 ± 1.1
NS
Native thiol (μmol/L)
270.7 ± 68.1
386.5 ± 58.5
<0.001
Total thiol (μmol/L)
300.6 ± 66.8
406.9 ± 60.2
<0.001
Disulphide (μmol/L)
18.6 ± 4.5
10.5 ± 3.3
<0.001
Disulphide/native thiol (%)
7.3 ± 3.1
2.7 ± 0.9
<0.001
Disulphide/total thiol (%)
6.1 ± 2.2
2.5 ± 0.8
<0.001
Native thiol/total thiol (%)
87.2 ± 5.1
94.9 ± 1.6
<0.001
statistical significance. Parameters were expressed as mean ± SD and median (interquartile range (IQR)). BMI: body mass index (kg/m2); WBC: white blood cell; CRP: C-reactive protein.