Research Article

A Novel Oxidative Stress Mediator in Acute Appendicitis: Thiol/Disulphide Homeostasis

Table 1

The demographics and laboratory findings of AA and control groups.

VariablesAcute appendicitisControl value
() ()

Gender, (%)
 Male43 (60.6)30 (42.3)0.04
 Female28 (39.4)41 (57.7)
Age (years)32.4 ± 9.130.1 ± 8.9NS
BMI (kg/m2)21.7 ± 2.923.8 ± 3.1NS
WBC (μL)13.5 ± 2.77.1 ± 1.5<0.001
CRP (mg/L)1.3 (18)0.6 (3)<0.001
Hemoglobin (g/dL)13.6 ± 0.913.6 ± 1.1NS
Native thiol (μmol/L)270.7 ± 68.1386.5 ± 58.5<0.001
Total thiol (μmol/L)300.6 ± 66.8406.9 ± 60.2<0.001
Disulphide (μmol/L)18.6 ± 4.510.5 ± 3.3<0.001
Disulphide/native thiol (%)7.3 ± 3.12.7 ± 0.9<0.001
Disulphide/total thiol (%)6.1 ± 2.22.5 ± 0.8<0.001
Native thiol/total thiol (%)87.2 ± 5.194.9 ± 1.6<0.001

statistical significance.
Parameters were expressed as mean ± SD and median (interquartile range (IQR)).
BMI: body mass index (kg/m2); WBC: white blood cell; CRP: C-reactive protein.