15-Lipoxygenase-1 Is Involved in the Effects of Atorvastatin on Endothelial Dysfunction

Figure 4

Effects of PD146176 (20 μM) and Lv-shALOX15 on expression levels of VCAM-1, ICAM-1, AKT, and eNOS in HUVECs. (a) and (b) Western blot analysis of VCAM-1/ICAM-1 in HUVECs. (c) and (d) Western blot analysis of AKT/eNOS in HUVECs. Results are expressed as mean ± SD. NC: normal control group. , , and versus the NC group; , , and versus the ox-LDL group or ox-LDL + Lv-GFP group. per group.

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