Plasma Leptin Is Elevated in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Figure 1

Plasma leptin and KL-6 concentrations in normal controls, S-IPF, and AE-IPF patients. (a) Plasma leptin concentrations were elevated significantly in AE-IPF patients when compared with S-IPF patients and healthy controls by ELISA ( and , resp.). Plasma leptin in S-IPF patients was also increased significantly compared with normal controls (). (b) Plasma KL-6 levels were enhanced significantly in AE-IPF patients compared with S-IPF patients and healthy controls ( and , resp.). Plasma KL-6 in S-IPF patients was also significantly higher than that in normal controls (). , .

(a)

(b)