Plasma Leptin Is Elevated in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Table 3

Cox proportional hazards models for time-to-death among 62 patients with IPF.

Clinical variables	Univariate model			Multivariate model
	HR	95% CI	value	HR	95% CI	value
Age (>70 yrs old)	0.495	0.247–0.992	0.048	0.647	0.312–1.345	0. 244
Leptin (>13.79 ng/mL)	0.358	0.175–0.734	0.005	0.328	0.153–0.705	0.004
PaO2/FiO2 (<300)	0.255	0.124–0.524	<0.001	0.256	0.124–0.530	<0.001