Caffeoylquinic Acid Derivatives Extract of Erigeron multiradiatus Alleviated Acute Myocardial Ischemia Reperfusion Injury in Rats through Inhibiting NF-KappaB and JNK Activations

Figure 5

Effects of AE on TNF-α and IL-6 after myocardial I/R in cardiac tissue. Hearts were subjected to 30 min ischemia followed by 24-hour reperfusion. (a) TNF-α. (b) IL-6. Different doses of AE (10, 20, or 40 mg/kg), CAPE 5 mg/kg, or saline (1 mL/kg) were administered via the tail vein 1 min before reperfusion. /group. , versus Sham; versus I/R vehicle.

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(b)