Caffeoylquinic Acid Derivatives Extract of Erigeron multiradiatus Alleviated Acute Myocardial Ischemia Reperfusion Injury in Rats through Inhibiting NF-KappaB and JNK Activations

Figure 7

Effects of AE on histopathological changes after I/R in hearts. (a–f) Left ventricular sections stained with hematoxylin and eosin from representative rats are shown (×20, arrowheads, leukocytes infiltration). (a) Sham. (b–f) Hearts were subjected to 30 min ischemia followed by 24-hour reperfusion. Saline ((b), 1 mL/kg), CAPE 5 mg/kg 40 mg/kg (c), or different doses of AE (10, 20, or 40 mg/kg) were administered via the tail vein 1 min before reperfusion. (g) Number of infiltrated leukocytes, 10 fields per heart specimen. (h) MPO activities. , versus Sham; versus I/R vehicle; . in each group. Leucocyte infiltration ▲.

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