Effects of ACL Reconstructive Surgery on Temporal Variations of Cytokine Levels in Synovial Fluid

Table 1

Cytokine levels in synovial fluids from longitudinal ACL group and from chronic ACL tear group.

	IL-6 (pg/mL)	IL-8 (pg/mL)	TNF-α (pg/mL)	IL-10 (pg/mL)	IL-1β (pg/mL)
Longitudinal ACL group
Acute samples	612.19 ± 124.98	362.3 ± 164.60	1.35 ± 0.52	29.09 ± 1.19	9.07 ± 5.18
Presurgery samples	163.34 ± 106.35	38.22 ± 26.05	2.47 ± 0.56	8.82 ± 2.05	12.94 ± 6.35
Postsurgery samples	855.37 ± 183.12	407.48 ± 109.71	2.4 ± 0.48	11.21 ± 2.03	9.42 ± 3.07
Chronic ACL tear group
Samples	58.52 ± 5.86	23.66 ± 1.55	6.15 ± 0.45	4.03 ± 0.21	6.15 ± 0.81

Cytokine concentrations (pg/mL) in the synovial fluid of patients of the longitudinal group () and chronic ACL tears (). Samples of longitudinal group were further assigned to groups according to the moment of the synovial fluid collection: acute samples (less than 72 hours after ACL injury); presurgery samples (1 month after the trauma, just before the arthroscopic ACL reconstruction surgery); postsurgery samples (1 month after the surgery). Values are expressed as mean ± standard error of the mean (SEM). Statistically significant periacute samples in comparison with chronic ACL tear group.