Disruption of Tumor Necrosis Factor Receptor-Associated Factor 5 Exacerbates Murine Experimental Colitis via Regulating T Helper Cell-Mediated Inflammation

Figure 3

Analysis of the mRNA expression of cytokines and transcription factors for Th cells in the colons of TRAF5 KO and WT mice. (a) TNF-α, (b) IFN-γ, (c) IL-4, (d) IL-17a, (e) IL-22, (f) T-bet, (g) GATA-3, (h) ROR-α, and (i) ROR-γt mRNA expression levels were determined by real-time PCR. The data are representative of 3 independent experiments (mean ± SD). per group. versus the DSS-treated WT group; versus the DSS-treated WT group. NS: not significant versus the DSS-treated WT group.

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