Disruption of Tumor Necrosis Factor Receptor-Associated Factor 5 Exacerbates Murine Experimental Colitis via Regulating T Helper Cell-Mediated Inflammation

Figure 6

Deficiency in TRAF5 augments the activation of NF-κB signaling. The phosphorylated and total protein expression levels of p65 and IκBα were detected in the colons of TRAF5 KO and WT mice. (a) Representative blots. ((b), (c), (d), and (e)) Quantitative results. The data are representative of 3 independent experiments (mean ± SD). per group. versus the DSS-treated WT group; versus the DSS-treated WT group. NS: not significant versus the DSS-treated WT group.

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