Research Article
Disruption of Tumor Necrosis Factor Receptor-Associated Factor 5 Exacerbates Murine Experimental Colitis via Regulating T Helper Cell-Mediated Inflammation
Table 2
Histological scoring system used in this study.
| Point | Epithelial damage | Inflammatory cell infiltration |
| 0 | Normal morphology | No infiltrate | 1 | Loss of goblet cells | Infiltrate around crypt base | 2 | Loss of goblet cells in large areas | Infiltrate reaching the L. muscularis mucosae | 3 | Loss of crypts | Extensive infiltration reaching the L. muscularis mucosae and thickening of the mucosa with abundant edema | 4 | Loss of crypts in large areas | Infiltration of the L. submucosa |
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