Icariin Prevents Cartilage and Bone Degradation in Experimental Models of Arthritis

Figure 2

TEM micrographs of chondrocytes and numbers of organelles in chondrocytes were counted to evaluate chondrocytes degeneration. (a) Normal group, (b) AIA group, (c) ICA group, and (d) control group (×10,000 magnification). F, filopodia; G, Golgi; N, euchromatin nucleus; M, mitochondria; RER, rough endoplasmic reticulum. The numbers of mitochondria (e) and Golgi bodies (f) were significantly decreased in the AIA group compared with those in the normal group (), whereas the numbers of mitochondria and Golgi were greatly increased in the ICA group (). However, when compared with the AIA group, the levels present in the IND positive control rabbits did not attain statistical significance. Results are presented as mean ± SD. , versus corresponding group.

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