Infection with Opportunistic Bacteria Triggers Severe Pulmonary Inflammation in Lupus-Prone Mice

Figure 5

Bacteria-specific T cell responses in lupus-prone mice. Ten days after Hi infection, B6 and B6/lpr mice were sacrificed. Lung and spleen cells were isolated and stimulated with heat-killed Hi. Cytokine productions by CD4 and γδ T cells were determined by intracellular staining. (a, b) IFN-γ and IL-17 produced by CD4 T cells from the lung and spleen. (c, d) Percentages of IFN-γ and IL-17 secreting γδ T cells from the lung and spleen. Data were expressed as . mice for each treatment group. ; . ns: no significant difference. This experiment is representative of three individual experiments.

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