METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway

Figure 4

METTL3 inhibited the proliferation and activation of pTHP-1 cells. (a) CCK-8 assay detecting the proliferation of cells at 0 hr, 12 hrs, 24 hrs, and 48 hrs (; ; ). (b) Decreased mRNA levels of IL-6 and TNF-α in METTL3-overexpressed pTHP-1 cells (; ; ). (c) Decreased levels of IL-6 and TNF-α protein in the cultural supernatant of METTL3-overexpressed cells (; and ).

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