Immunological Dynamics Associated with Direct-Acting Antiviral Therapies in Naive and Experimented HCV Chronic-Infected Patients

Table 2

Hematological and biochemical characteristics of the control group, before (BT) and after (AT) treatment.

Characteristics	Control group ()	HCV patients		value
		BT ()	AT ()
Hematologic ()
WBC ()				<0.0043^a; <0.0012^b
RBC ()				<0.0001^a,b
Hb (g/dl)				<0.0003^a; <0.0001^b
Ht (%)				<0.0001^a,b
MCV (fl)				0.2033^a,b
MCH (pg)				0.1105^a,b
MCHC (g/dl)				0.1661^a,b
RDW (%)				0.2836^a,b
PLT ()				<0.0001^a,b
Biochemical (mean ± SD)
	Reference value	BT ()	AT ()	value
AST (UI/l)	5-40			0.0660
ALT (UI/l)	10-55			0.0162
BT (mg/dl)	0.1-1.2			0.7403

^#Kruskal-Wallis test; SD: standard deviation; WBC: white blood cells; RBC: red blood cells; Ht: hematocrit; Hb: hemoglobin; MCV: mean corpuscular volume; MCH: medium corpuscular hemoglobin; CHCM: mean corpuscular hemoglobin concentration; RDW: red cell distribution width; PLT: platelet; AST: aspartate aminotransferase; ALT: alanine aminotransferase. ^aComparison of the control group with BT patients; ^bcomparison of the control group with AT patients, nonparametric -test application and Mann–Whitney. Reference value : retrieved from results of biochemical tests of kits.