Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: A Comparative Study

<div>High-salt diet induced changes in integrin CD11b(act)/Mac-1, CD11a/LFA-1, and CD49d/VLA-4 expression on peripheral blood leukocyte subsets in young healthy subjects. Representative dot plots illustrating gating strategy, including exclusion of doublets using forward scatter area (FSC-A) versus forward scatter width (FSC-W) analysis; gating on CD45+ leukocytes; and gating for lymphocyte, monocyte, and granulocyte subpopulations are shown in (a). Representative histograms demonstrating integrin expression during LS and HS diets are shown for CD11b/Mac-1 (b), CD11a/LFA-1 (c), and CD49d/VLA-4 (d).</div>

Mediators of Inflammation

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Figure 1

Figure 1: Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: A Comparative Study 

Figure 1 | Short-Term High-NaCl Dietary Intake Changes Leukocyte Expression of VLA-4, LFA-1, and Mac-1 Integrins in Both Healthy Humans and Sprague-Dawley Rats: A Comparative Study 