Apolipoprotein A-V Is a Novel Diagnostic and Prognostic Predictor in Pediatric Patients with Sepsis: A Prospective Pilot Study in PICU
Table 1
Baseline characteristics of patients with sepsis.
Total ()
Survivor ()
Nonsurvivor ()
Age (month)
19 (5-60)
19 (7-62)
5 (2.5-45)
0.357
Body weight (kg)
12 (7.5-18.75)
12 (8-19)
7.5 (6-15.5)
0.217
Gender (male, %)
58
54
4
0.134
From emergency
71
66
5
0.056
Respiratory rate (/min)
36 (30-46)
35 (28-45)
40.5 (38-60)
0.101
Heart rate (beats/min)
150 (121-179)
150 (120-175)
160 (150-198)
0.100
MAP (mmHg)
86 (75.7-97.3)
86 (74.6-96.7)
92 (80-107)
0.208
SBP (mmHg)
101 (88-112)
100.5 (88-112)
102 (92-115)
0.563
PRISM III
6 (2-12)
6 (2-10)
13 (5-21)
0.007
Co-morbidities
Respiratory failure, (%)
60 (59.4)
49 (54.4)
11 (100)
0.004
Shock, (%)
45 (44.6)
35 (38.9)
10 (90.9)
0.001
Gastrointestinal disorder, (%)
35 (34.7)
29 (32.2)
6 (54.5)
0.142
Liver injury, (%)
11 (10.9)
7 (7.8)
4 (36.4)
0.004
Acute kidney injury, (%)
17 (16.8)
15 (16.7)
2 (18.2)
0.899
Infection site
0.491
Respiratory system,
52
45
7
Gastrointestinal system,
24
23
1
Urine system,
1
1
0
Skin and soft tissue,
1
1
0
Central nervous system,
14
11
3
aOthers,
9
9
0
Pathogen
0.887
Bacterial,
57
51
6
Virus,
29
25
4
Fungi,
2
2
0
bOthers,
13
12
1
Mechanical ventilator, (%)
53 (52.5)
42 (46.7)
11 (100)
< 0.001
Vasoactive agents, (%)
54 (53.7)
43 (47.8)
11 (100)
0.001
Length of PICU stay (day)
13 (8-21)
13 (8-20)
17 (4-29)
0.711
MAP: mean arterial pressure; SBP: systolic blood pressure; PRISM III: pediatric risk of mortality III; aOthers: more than one infection site found in the patient; bOthers: mixed infection, more than one pathogen species found in the patient.
