Inflammation plays a major role in the formation and in the progression of several chorioretinal diseases. A variety of factors are then released into the vitreous cavity, which can be more easily accessed for diagnostic purposes. Advances in the analysis of vitreous humour samples have highlighted new biological mechanisms of long-known diseases, providing a new perspective for therapeutic strategies. The analysis of vitreous samples is also instrumental for the differential diagnosis of inflammatory versus infective or neoplastic diseases of the eye. We particularly take an interest in manuscripts that report relevance of vitreous samples analyses for improved diagnosis, prognosis, or monitoring of therapy. Potential topics include, but are not limited to:

• Proteomic analyses of the vitreous humour
• Profile of lipid and soluble factor in diabetic retinopathy
• Vitreous mediators in retinal hypoxic disease
• Mechanism of inflammation in age-related macular degeneration
• Mediators of inflammation in proliferative vitreoretinal disease
• Vitreous diagnosis in neoplastic disease
• Vitreous tap analysis in the management of uveitis
• Intravitreal devices in treatment of vitreous inflammation
• Systemic treatment of vitreous inflammation

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