It has long been recognized that allergic inflammation is the fundamental pathological changes of allergy. Soluble allergens, sIgE, and mast cells or basophils are three key factors of allergy, representing causative factors, messenger, and primary effector cells, respectively. Eosinophils and neutrophils are secondary effector cells. However, some new receptors such as protease activated receptors and toll-like receptors, new “messengers” including IgG, IL-17, and IL-33, novel cell types such as regulatory T cells and regulatory B cells, and varieties of novel allergens have been discovered in recent years, which makes the current understandings of the mechanisms of allergy even more confusing.

We invite authors to present original research articles as well as review articles that will add new information in discovering the actions of allergens and proinflammatory mediators in allergy. We are particularly interested in manuscripts that report the roles of mast cells, basophils, T cells, dentritic cells, eosinophils, neutrophils, B cells, and epithelial cells in allergy and potential clinical therapies in these respects, but reports on other cell types are also welcomed. Reviews that summarize the results of latest progresses and views on allergy are particularly welcomed. Potential topics include, but are not limited to:

• A new look into allergic diseases
• Influence of allergens and proinflammatory mediators on mast cells and basophils
• Influence of allergens and proinflammatory mediators on eosinophils and neutrophils
• Influence of allergens and proinflammatory mediators on T cells and B cells
• Influence of allergens and proinflammatory mediators on dentritic cells
• Discovering novel allergens in allergy
• Mechanisms of allergen-induced allergic reactions
• Allergies to multiple environmental determinants and environmental chemical hypersensitivities, for example, multiple chemical sensitivity
• Molecule and cell based development of diagnosing tests for allergic diseases
• Pathophysiology, clinical diagnoses, and treatment of allergic diseases, for example, rhinitis, asthma, urticaria, and so forth

Before submission, authors should carefully read the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/mi/aama/ according to the following timetable: