Recent studies have revealed the link of the newly identified inflammation mediators to the pathogenesis of cancer and chronic inflammatory diseases, such as diabetes mellitus and chronic kidney disease, and the important role of inflammation in the tissue repair or wound healing. This issue will focus on the recent discoveries of the inflammation mediators in these fields of research. Knowledge and understanding of these inflammation mediators and the mechanisms of their actions in each condition of human diseases will lead to the development of novel therapies against these health problems.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to identify the key inflammation mediators associated with cancer, chronic inflammatory diseases, and tissue damage/repair particularly in clinical setting and to reveal the mechanisms by which the inflammation mediators induce the inflammatory pathologies in animal models. We are particularly interested in articles describing the new discovery in the clinical characterization of the inflammation mediators in chronic inflammatory diseases as well as ‘nontraditional’ inflammatory diseases, such as cancer and diabetes. We are also interested in new hypothesis regarding the regulation and mechanisms of inflammation mediators in the development of chronic inflammatory diseases.

Potential topics include, but are not limited to:

• Inflammation in cancer
• Recent advances in the research of chronic inflammatory diseases
• Acute and chronic inflammation and tissue repair