Minimally Invasive Local Treatments for Bone and Pulmonary Metastases

Table 4

Summary of RFA studies in metastatic disease.

Author	Primary tumor	Number of patients	Median followup	Outcomes	Most common toxicity
Yamakado et al. [42]	Colorectal	71	19 (mean)	3 yr OS: 46%; Intrapulmonary recurrence: 47%	Pneumothorax (47%)
Nakamura et al. [43]	Sarcoma	20	18 mo.	1 yr OS: 88%; 3 yr OS: 29%; Incomplete ablation: 45%	Pneumothorax (65%)
Palussière et al. [44]	Sarcoma	29	50 mo.	1 yr OS: 92.2%; 2 yr OS: 65.2%; Incomplete ablation: 10%	Pneumothorax (67.8%)
Yan et al. [45]	Colorectal	55	24 mo.	1 yr OS: 85%; 2 yr OS: 64%; PFS: 15 mo.	Pneumothorax (29%)
King et al. [46]	Colorectal	19	24.3 mo.	1 yr LC: 90%	Pneumothorax (52%)