Multiobjective Optimal Control of HIV Dynamics

Table 1

Parameter values for the HIV model.

Parameters	Value/unit	Description
𝑠	7 cells μL^-1 day^-1	Production(source) rate of CD4+ T-cells
𝑑	7×10^−3 day^-1	Death rate of uninfected CD4+ T-cell population
𝑎	0.0999 day^-1	Infected CD4+ T-cell death rate
𝑓	2 μL cells^-1 day^-1	Rate at which infected cells are killed by CTL effectors
𝑐	5×10^−6 μL^2 cells^-2 day^-1	Proliferation rate of CTL precursors
𝑞	6×10^−4 μL cells^-1 day^-1	Rate at which CTL effectors are produced from CTL precursors
𝑏	0.017 day^-1	Death rate of CTL precursors
ℎ	0.06 day^-1	Death rate of CTL effectors
𝑘	300 copies mL^-1 cells^-1 μL day^-1	Rate at which virus is produced from infected cells.
𝜏	0.2 day^-1	Virus natural death rate
𝑟0	10^-9 copies^-1 mL day^-2	Aggressiveness growth rate of the virus