Research Article

Estimating Network Kinetics of the MAPK/ERK Pathway Using Biochemical Data

Table 13

List of proteins used in inference of the reaction rates of Model 5.

Independent Ras.GDP, Ras.GTP, Raf, Raf.I, Raf. , Raf.A-Ras.GT , Raf.I-RKIP,
Raf.I-RKI , Raf.I-RKIP-Ras.GT , MEK, ME , ME , MEK.p2,
MEK-RKIP, ME -RKIP, ME -RKIP, ERK, ERK.p1, ERK.p2,
ERK.p2-TF.p2, ERK.p2-RSK.A, Grb2, Shc, Sh , SOS, Grb2-SOS,
Grb2-SO , c-Fos, c-Fos.RNA, c-Fos.p, MKP, MKP.RNA, EGFR, RKIP

Dependent Raf. , Raf.I-Ras.GT , MEK.p2-RKIP, ERK.p2-RSK.A-TF.p2, Grb ,
Shc-Grb2-SO , Shc-Grb , MKP.DNA, TF, GAP, PP2A, PAK, PP5,
PKC, RSK, c-Fos.DNA, RKIP.p