Research Article

Estimating Network Kinetics of the MAPK/ERK Pathway Using Biochemical Data

Table 6

List of proteins used in inference of the reaction rates of Model 1.

Independent Ras.GDP, Ras.GTP, Raf, Raf.I, Raf. , MEK, , MEK.p2
ERK, ERK.p2, ERK.p2-TF.p2, ERK.p2-RSK.A, Grb2, Shc, SOS,
Grb2-SOS, Grb2- , c-Fos, c-Fos.RNA, MKP.

Dependent Raf. , Raf.I-Ras. , , ERK.p2-RSK.A-TF.p2, ,
Shc-Grb2- , Shc- , c-Fos.p, c-Fos.DNA, MKP.DNA,
MKP.RNA, EGFR, TF, GAP, PP2A, PAK, PP5, RSK.