Clinical Efficacy of Artemether-Lumefantrine in Congolese Children with Acute Uncomplicated Falciparum Malaria in Brazzaville

Table 1

Baseline characteristics of patients before treatment with artemether-lumefantrine.

Number of patients	77
Age (years), mean ± SD (range)	4.5 ± 2.4 (8 months–10 years)
Number of patients <5 years old	42 (54.5%)
Number of patients aged 5–10 years old	35 (45.5%)
Weight (kg), mean ± SD (range)	15.9 ± 5.4 (8–28)
Sex ratio (F/M)	39/38 (1.03)
Number of patients who took an antimalarial drug before inclusion	14 (18.2%)*
Body temperature, mean ± SD (range)	38.1 ± 0.8 (36.0–40.3)**
Parasite density (asexual parasites/𝜇L)
Overall geometric mean (range), (95% CI)	33,300 (2,450–381,000), [28,200–38,500]
Number of patients with parasite density > 200,000 asexual parasites/μL	2 (2.8%)
Geometric mean (range), (95% CI) in patients <5 years old	35,000 (3,480–213,000) [14,100–55,200]
Geometric mean (range) (95% CI) in patients 5–10 years old	33,700 (2,450–381,000) [8,990–58,400]
Haematocrit (%) mean (range), (95% CI)	32.6 (20–40) [31.6–33.8]

SD: standard deviation; 95% CI: 95% confidence intervals; *eight patients received chloroquine; 6 received quinine; **two patients had fever within 24 hr before consultation but were no longer febrile at the time of consultation.