Comparative Study on the Effects of Chloroquine and Artesunate on Histopathological Damages Caused by Plasmodium berghei in Four Vital Organs of Infected Albino Mice

Table 1

Histopathological effects on the liver.

Pathological effects	Treatment		Control
	CQ	ART	INT
Kupffer cell hyperplasia	++	−	++++
Haemosiderosis	++	−	++++
Hepatic necrosis	++	++	++++
Periportal mononuclear cells infiltration	+	+	−

CQ: chloroquine, ART: artesunate, INT: infected but not treated. Not present (−), very mild (+), mild (++), moderate (+++), and severe (++++).